H Rogier van Doorn
The Oxford University Clinical Research Unit-Vietnam (OUCRU) was established in Ho Chi Minh City in 1991. It is hosted by the Hospital for Tropical Diseases (HTD), originally founded in 1862. HTD is the referral hospital for infectious diseases for all of southern Viet Nam.
Our strategic aim is to have a positive and significant impact on global health and, in particular, the prevention, diagnosis and treatment of infectious diseases. This is being achieved via an integrated long-term research programme, contributions to training, the scientific literature, national and international meetings and membership of national and international committees. OUCRU is one of five Wellcome Programmes.
The Oxford University Clinical Research Unit, Hanoi (OUCRU) was established in 2006 and is hosted by the National Hospital of Tropical Diseases (NHTD). NHTD is a tertiary care centre for infectious diseases in northern Viet Nam and unlike most hospitals is a specialist hospital under the direct supervision of the Ministry of Health. OUCRU’s research programme puts clinical and public health research at the centre of its integrated clinical science programme.
In addition to NHTD, OUCRU Hanoi works closely with many hospitals across northern Viet Nam and, in particular with the National Institute for Hygiene and Epidemiology. OUCRU Hanoi has state-of-the-art diagnostic and research capabilities which improve the prevention, diagnosis and treatment of major infectious diseases.
The research programme at OUCRU Hanoi focuses on clinical and epidemiological aspects of respiratory infections (both bacterial and viral), antimicrobial resistance, zoonosis (including Streptococcus suis) and dengue. Furthermore, OUCRU Hanoi is studying zoonotic infections in collaboration with Hanoi Medical University as part of the VIZIONS project. Through NHTD OUCRU Hanoi has also been involved in consultations with the Ministry of Health on antibiotic treatment guidelines, management of avian influenza and Streptococcus suis, and other public health issues.
The importance of OUCRU Hanoi in Viet Nam
OUCRU Hanoi is close to all the key national institutes in Vietnam (see partners/collaborators) and the Ministry of Health. These relations ensure that OUCRU research findings also find their way into policies. Our research in the area of antibiotic resistance supported the development of a National Action Plan on Antibiotic Resistance that was signed by the Minister of Health mid 2013.
Our research locations
OUCRU Hanoi is based at the National Hospital of Tropical Diseases and we also have research offices and laboratory capacity at the National Institute of Hygiene and Epidemiology (NIHE), National Hospital of Paediatrics and Hanoi Medical University (HMU). With NIHE we now conduct influenza household transmission studies for over 8 years in Ha Nam. With HMU we conduct community based studies in Ba Vi and Dong Da.
OUCRU Ha Noi Ph D / D Phil STUDENTS
- Huong Vu Thi Lan, Public Health Masters. Huong works on the burden of Streptococcus suis infections in Vietnam and risky food behaviour.
- Do thi Thuy Nga, Pharmacist. Nga works on strategies to reduce antibiotic use in Vietnam.
- Vu Dinh Phu, clinician and head of ICU NHTD. Dr Phu works on hospital acquired infections on ICUs in Vietnam
- Tran Thi Sinh, Microbiologist at NHP. Sinh works on improving laboratory diagnosis of pediatric tuberculosis.
- Nguyen thi Diep, Veterinarian at National Center for Veterinary Diagnosis. Diep works on poultry antibody landscapes of avian influenza.
- National Hospital of Tropical Diseases
- National Institute of Hygiene and Epidemiology
- Hanoi Medical University
- National Hospital of Pediatrics
- National Center for Veterinary Diagnosis
- National Lung hospital
We recently completed a national program (VINARES) to assess hospital acquired infections, antibiotic use and antibiotic resistance in 16 hospitals across Vietnam. We had a closing meeting in October 2013 with 120 international participants in Hanoi.
OUCRU Ha Noi has brought together NICE International and the Vietnamese Ministry of Health to establish a working process to design and implement evidence-based guidelines for AMR
OUCRU Ha Noi has obtained funding from the Fleming Fund UK and a mandate from the Vietnamese Ministry of Health to establish a National Reference Laboratory and Surveillance Network for Antimicrobial Resistance with the National Hospital of Tropical Disease
We are running one of the longest influenza household cohorts worldwide in Ha Nam, Vietnam. This cohort has been ongoing for over 8 years leading to new knowledge in the area of influenza transmission and immunology.
ACORN (A Clinically-Oriented Antimicrobial Resistance Surveillance Network): a pilot protocol for case based antimicrobial resistance surveillance
Turner P. et al, (2020), Wellcome Open Research, 5, 13 - 13
Case-based surveillance of antimicrobial resistance in the ACORN (A Clinically Oriented Antimicrobial Resistance Surveillance Network) study
van Doorn HR. et al, (2020), JAC-Antimicrobial Resistance, 2
Performance of Metagenomic Next-Generation Sequencing for the Diagnosis of Viral Meningoencephalitis in a Resource-Limited Setting.
Hong NTT. et al, (2020), Open Forum Infectious Diseases, 7
Does sunlight drive seasonality of TB in Vietnam? A retrospective environmental ecological study of tuberculosis seasonality in Vietnam from 2010 to 2015.
Bonell A. et al, (2020), BMC infectious diseases, 20
Neutralizing Antibodies against Enteroviruses in Patients with Hand, Foot and Mouth Disease.
Nguyet LA. et al, (2020), Emerging infectious diseases, 26, 298 - 306