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Adjuvants are key components used to enhance vaccine efficacy. Their use has been well characterised to stimulate antibody responses but very little has been investigated regarding their effect on cytotoxic T cell responses.

In this study, an extensive group of adjuvants has been assessed to investigate immunity enhancement against liver-stage malaria through stimulation of T cell responses. Two were found to improve vaccine efficacy against a sporozoite challenge and the mechanism is presented.

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