28 June 2019
A new study led by Professor Julian Knight at the Wellcome Centre for Human Genetics and colleagues from the ULTRA-DD Consortium shows how genetics and knowledge of networks can prioritise drug targets for immune-mediated diseases.
13 June 2019
Researchers from the University of Oxford, including NDM's Professor Simon Draper, along with partners from five institutions around the world, have identified the human antibodies that prevent the malaria parasite from entering blood cells, which may be key to creating a highly effective malaria vaccination.
14 May 2019
Hepatitis B virus (HBV) infects 290 million people worldwide. Oxford Nanopore Technology sequencing platforms provide potential for sequencing the whole HBV genome in a single read, facilitating improved insights into virus epidemiology, diversity, and pathogenesis.
A Novel Vaccine Strategy Employing Serologically Different Adenoviral Vectors for the Prevention of HIV-1 and HCV Coinfection
11 April 2019
Nearly 3 million people are co-infected with hepatitis C and HIV. Effective preventive strategies targeting both viruses are needed.
Assessment of Immunogenicity and Neutralisation Efficacy of Viral-Vectored Vaccines Against Chikungunya Virus
11 April 2019
Chikungunya virus (CHIKV) has caused explosive outbreaks in more than 60 countries. Infection can cause a long-term, debilitating disease characterised by joint inflammation and chronic arthritis lasting several years.
28 February 2019
A research team led by Prof Alison Simmons at MRC HIU and Professor of Gastroenterology used single-cell technology to identify new players in the gut epithelial barrier.
29 January 2019
Ludwig Institute's study of venous development by Professor Sarah De Val, identifying a new potential target for anti-angiogenic cancer therapy is now published in Nature Communications.
8 January 2019
Four out of five people in the world with diabetes now live in low and middle income countries.
Safety and immunogenicity of a heterologous prime-boost Ebola virus vaccine regimen - ChAd3-EBO-Z followed by MVA-EBO-Z in healthy adults in the UK and Senegal
7 December 2018
Vaccines against Ebola remain an urgent global health priority and outbreaks continue, notably the ongoing outbreak in North Kivu in the DRC.
16 November 2018
New analysis of the structure and function of the naturally-occurring antimicrobial agent tunicamycin has revealed ways to produce new, safe antibiotics for Mycobacterium tuberculosis and other disease-causing bacteria.
22 August 2018
Disease processes can switch genes on or off in a cell and this can alter the progress of the disease.
22 August 2018
Pneumothorax is a common condition which can affect anyone where air leaks from the lung and causes lung collapse.
2 August 2018
Ross Chapman and WTCHG colleagues have published their research in Nature which describes the discovery of the Shieldin complex, a single-stranded DNA-binding repair complex that is essential for context-dependent DNA repair events in the immune system and cancer.
Addressing challenges faced by insecticide spraying for the control of dengue fever in Bangkok, Thailand: a qualitative approach
24 July 2018
A study from Bangkok by Professor Wirichada Pan-Ngum and colleagues shows accessing households for proper spraying was a problem for control dengue outbreaks.
25 June 2018
The leading Oxford’s chimpanzee adenovirus vaccine platform has been engineered as a Zika vaccine, opening the door to clinical trials at the University of Oxford and Mexico.
Development and validation of response markers to predict survival and pleurodesis success in patients with malignant pleural effusion (PROMISE): a multicohort analysis
17 June 2018
The prevalence of malignant pleural effusion is increasing worldwide, but prognostic biomarkers to plan treatment and to understand the underlying mechanisms of disease progression remain unidentified.
11 June 2018
The Malaria Atlas Project has created a global map of the travel time to urban centers for the year 2015. Cities concentrate activities that promote human wellbeing including education, employment, and healthcare services.