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BARD1 reads H2A lysine 15 ubiquitination to direct homologous recombination

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Becker JR. et al, (2021), Nature, 596, 433 - 437

Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD

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Hewitt G. et al, (2021), Molecular Cell, 81, 767 - 783.e11

Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.

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Yeow ZY. et al, (2020), Nature, 585, 447 - 452

Functional Radiogenetic Profiling Implicates ERCC6L2 in Non-homologous End Joining.

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Francica P. et al, (2020), Cell reports, 32

An essential role for the Zn2+ transporter ZIP7 in B cell development

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Anzilotti C. et al, (2019), Nature Immunology, 20, 350 - 361

H4K20me0 recognition by BRCA1–BARD1 directs homologous recombination to sister chromatids

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Nakamura K. et al, (2019), Nature Cell Biology, 21, 311 - 318

H4K20meO recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids

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Nakamura K. et al, (2019), NATURE CELL BIOLOGY, 21, 311 - +

53BP1 cooperation with the REV7–shieldin complex underpins DNA structure-specific NHEJ

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Ghezraoui H. et al, (2018), Nature, 560, 122 - 127

Mechanism of 53BP1 activity regulation by RNA-binding TIRR and a designer protein

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Botuyan MV. et al, (2018), Nature Structural & Molecular Biology, 25, 591 - 600

53BP1 Integrates DNA Repair and p53-Dependent Cell Fate Decisions via Distinct Mechanisms.

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REV7 counteracts DNA double-strand break resection and affects PARP inhibition.

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