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Structural Premise of Selective Deubiquitinase USP30 Inhibition by Small-Molecule Benzosulfonamides

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O'Brien DP. et al, (2023), Molecular & Cellular Proteomics, 22, 100609 - 100609

Open drug discovery in Alzheimer's disease.

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Axtman AD. et al, (2023), Alzheimer's & dementia (New York, N. Y.), 9

Development of Selective ADAMTS-5 Peptide Substrates to Monitor Proteinase Activity

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Fowkes MM. et al, (2023), Journal of Medicinal Chemistry

Discovery and Development Strategies for SARS-CoV-2 NSP3 Macrodomain Inhibitors

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Schuller M. et al, (2023), Pathogens, 12, 324 - 324

Synthesis of meta-substituted arene bioisosteres from [3.1.1]propellane.

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Frank N. et al, (2022), Nature

Covalent fragment-based ligand screening approaches for identification of novel ubiquitin proteasome system modulators

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Rothweiler EM. et al, (2022), Biological Chemistry, 403, 391 - 402

Kalirin as a Novel Treatment Target for Cognitive Dysfunction in Schizophrenia

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Mould AW. et al, (2022), CNS Drugs, 36, 1 - 16

Target 2035-update on the quest for a probe for every protein

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Mueller S. et al, (2021), RSC MEDICINAL CHEMISTRY

The structural basis of fatty acid elongation by the ELOVL elongases

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Nie L. et al, (2021), Nature Structural & Molecular Biology, 28, 512 - 520

Fragment Screening Reveals Starting Points for Rational Design of Galactokinase 1 Inhibitors to Treat Classic Galactosemia

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Mackinnon SR. et al, (2021), ACS Chemical Biology, 16, 586 - 595

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