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Exploring the relevance of NUP93 variants in steroid-resistant nephrotic syndrome using next generation sequencing and a fly kidney model.

Journal article

Bierzynska A. et al, (2022), Pediatric nephrology (Berlin, Germany), 37, 2643 - 2656

NDRG1 is induced by antigen-receptor signaling but dispensable for B and T cell self-tolerance.

Journal article

Hodgson R. et al, (2022), Communications biology, 5

SARS-CoV-2-Specific T Cell Responses Are Not Associated with Protection against Reinfection in Hemodialysis Patients

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Shankar S. et al, (2022), Journal of the American Society of Nephrology, 33, 883 - 887

Neutralising antibodies after COVID-19 vaccination in UK haemodialysis patients

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Carr EJ. et al, (2021), The Lancet, 398, 1038 - 1041

Regular RNA screening detects asymptomatic SARS-CoV-2 infection in haemodialysis patients

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Storey B. et al, (2021), Nephrology Dialysis Transplantation, 36, 1130 - 1132

An ontogenetic switch drives the positive and negative selection of B cells

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Xu X. et al, (2020), Proceedings of the National Academy of Sciences, 117, 3718 - 3727

High-throughput phenotyping reveals expansive genetic and structural underpinnings of immune variation.

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Abeler-Dörner L. et al, (2020), Nature immunology, 21, 86 - 100

Systemic silencing of Phd2 causes reversible immune regulatory dysfunction

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Yamamoto A. et al, (2019), Journal of Clinical Investigation, 129, 3640 - 3656

An essential role for the Zn2+ transporter ZIP7 in B cell development

Journal article

Anzilotti C. et al, (2019), Nature Immunology, 20, 350 - 361

Interventions for chronic kidney disease in people with sickle cell disease

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Roy NBA. et al, (2017), Cochrane Database of Systematic Reviews, 2017

Themis2 lowers the threshold for B cell activation during positive selection

Journal article

Cheng D. et al, (2017), Nature Immunology, 18, 205 - 213

VEGF regulates local inhibitory complement proteins in the eye and kidney

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Keir LS. et al, (2016), Journal of Clinical Investigation, 127, 199 - 214

Mutation of Fnip1 is associated with B-cell deficiency, cardiomyopathy, and elevated AMPK activity

Journal article

Siggs OM. et al, (2016), Proceedings of the National Academy of Sciences, 113, E3706 - E3715

Current strategies for mutation detection in phenotype-driven screens utilising next generation sequencing

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Simon MM. et al, (2015), Mammalian Genome, 26, 486 - 500

Factors influencing success of clinical genome sequencing across a broad spectrum of disorders

Journal article

Taylor JC. et al, (2015), Nature Genetics, 47, 717 - 726

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