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Publications

Decoding Allosteric Control in Hypoxia-Inducible Factors.

Zhuang J. et al, (2023), Journal of molecular biology

Identification of oleoylethanolamide as an endogenous ligand for HIF-3α.

Diao X. et al, (2022), Nature communications, 13

Marked and rapid effects of pharmacological HIF-2α antagonism on hypoxic ventilatory control

Cheng X. et al, (2020), Journal of Clinical Investigation, 130, 2237 - 2251

Author Correction: Bile acid metabolites control TH17 and Treg cell differentiation.

Hang S. et al, (2020), Nature, 579

Chemical Proteomics and Phenotypic Profiling Identifies the Aryl Hydrocarbon Receptor as a Molecular Target of the Utrophin Modulator Ezutromid.

Wilkinson IVL. et al, (2020), Angewandte Chemie (International ed. in English), 59, 2420 - 2428

Bile acid metabolites control TH17 and Treg cell differentiation.

Hang S. et al, (2019), Nature, 576, 143 - 148

Bidirectional modulation of HIF-2 activity through chemical ligands.

Wu D. et al, (2019), Nature chemical biology, 15, 367 - 376

Vitamin D Binding Protein: A Historic Overview.

Bouillon R. et al, (2019), Frontiers in endocrinology, 10

Retraction Note: DDX5 and its associated lncRNA Rmrp modulate TH17 cell effector functions

Huang W. et al, (2018), Nature, 562, 150 - 150

The Nuclear Receptor PPARγ Controls Progressive Macrophage Polarization as a Ligand-Insensitive Epigenomic Ratchet of Transcriptional Memory

Daniel B. et al, (2018), Immunity, 49, 615 - 626.e6

A nonalcoholic fatty liver disease model in human induced pluripotent stem cell-derived hepatocytes, created by endoplasmic reticulum stress-induced steatosis

Parafati M. et al, (2018), Disease Models & Mechanisms, 11

The quaternary architecture of RARβ–RXRα heterodimer facilitates domain–domain signal transmission

Chandra V. et al, (2017), Nature Communications, 8

Tapinarof Is a Natural AhR Agonist that Resolves Skin Inflammation in Mice and Humans

Smith SH. et al, (2017), Journal of Investigative Dermatology, 137, 2110 - 2119

Structural characterization of mammalian bHLH-PAS transcription factors

Wu D. and Rastinejad F., (2017), Current Opinion in Structural Biology, 43, 1 - 9

Small Molecule Inhibitor of NRF2 Selectively Intervenes Therapeutic Resistance in KEAP1-Deficient NSCLC Tumors

Singh A. et al, (2016), ACS Chemical Biology, 11, 3214 - 3225

Visualizing the Architectures and Interactions of Nuclear Receptors

Khorasanizadeh S. and Rastinejad F., (2016), Endocrinology, 157, 4212 - 4221

NPAS1-ARNT and NPAS3-ARNT crystal structures implicate the bHLH-PAS family as multi-ligand binding transcription factors

Wu D. et al, (2016), eLife, 5

Erratum: Corrigendum: DDX5 and its associated lncRNA Rmrp modulate TH17 cell effector functions

Huang W. et al, (2016), Nature, 533, 130 - 130

DDX5 and its associated lncRNA Rmrp modulate TH17 cell effector functions

Huang W. et al, (2015), Nature, 528, 517 - 522

Structural integration in hypoxia-inducible factors

Wu D. et al, (2015), Nature, 524, 303 - 308

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