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Structural Analysis and Development of Notum Fragment Screening Hits.

Journal article

Zhao Y. et al, (2022), ACS chemical neuroscience

The guidance and adhesion protein FLRT2 dimerizes in cis via dual small-X3-small transmembrane motifs.

Journal article

Jackson V. et al, (2022), Structure (London, England : 1993)

Quantitative SARS-CoV-2 anti-spike responses to Pfizer–BioNTech and Oxford–AstraZeneca vaccines by previous infection status

Journal article

Eyre DW. et al, (2021), Clinical Microbiology and Infection, 27, 1516.e7 - 1516.e14

NOTUM from Apc-mutant cells biases clonal competition to initiate cancer.

Journal article

Flanagan DJ. et al, (2021), Nature

Small-molecule inhibitors of carboxylesterase Notum

Journal article

Zhao Y. et al, (2021), Future Medicinal Chemistry

Notum Deacylates Octanoylated Ghrelin

Journal article

Zhao Y. et al, (2021), Molecular Metabolism, 101201 - 101201

A variant in IL6ST with a selective IL-11 signaling defect in human and mouse

Journal article

Schwerd T. et al, (2020), Bone Research, 8

Caffeine inhibits Notum activity by binding at the catalytic pocket

Journal article

Zhao Y. et al, (2020), Communications Biology, 3

Hand-foot-and-mouth disease virus receptor KREMEN1 binds the canyon of Coxsackie Virus A10

Journal article

Zhao Y. et al, (2020), Nature Communications, 11

Structure of the Human Cation-Independent Mannose 6-Phosphate/IGF2 Receptor Domains 7-11 Uncovers the Mannose 6-Phosphate Binding Site of Domain 9.

Journal article

Bochel AJ. et al, (2020), Structure (London, England : 1993), 28, 1300 - 1312.e5

A variant in IL6ST with a selective IL-11 signaling defect in human and mouse.

Journal article

Schwerd T. et al, (2020), Bone research, 8

Structural basis of semaphorin‐plexin cis interaction

Journal article

Rozbesky D. et al, (2020), The EMBO Journal

Antiepileptic Drug Carbamazepine Binds to a Novel Pocket on the Wnt Receptor Frizzled-8

Journal article

Zhao Y. et al, (2020), Journal of Medicinal Chemistry, 63, 3252 - 3260

Drosophila OTK Is a Glycosaminoglycan-Binding Protein with High Conformational Flexibility.

Journal article

Rozbesky D. et al, (2020), Structure (London, England : 1993)

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