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As global malaria mortality increases the urgency for vaccine development, analysis of immune responses in naturally exposed populations is providing clues to the nature of protective immunity. Recently, sophisticated immune evasion strategies adopted by the parasite have been analysed at the molecular level. More immunogenic vaccination strategies have been identified, providing renewed optimism that effective malaria control through vaccination should be feasible.

Type

Journal article

Journal

Curr Opin Immunol

Publication Date

08/2000

Volume

12

Pages

437 - 441

Keywords

Animals, Endemic Diseases, Erythrocytes, Hematopoietic Stem Cells, Humans, Malaria