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The initial treatment regime for primary spontaneous pneumothorax (PSP) is generic and non-personalised, often involving a long hospital stay waiting for air leak to cease. This prospective study of 81 patients with PSP, who required drain insertion, captured daily digital air leak measurements and assessed failure of medical management against prespecified criteria. Patients with higher air leak at day 1 or 2 had significantly longer hospital stay. If air leak was ≥100 mL/min on day 1, the adjusted OR of treatment failure was 5.2 (95% CI 1.2 to 22.6, p=0.03), demonstrating that early digital air leak measurements could potentially predict future medical treatment failure. TRIAL REGISTRATION NUMBER: ISRCTN79151659.

Original publication

DOI

10.1136/thoraxjnl-2018-212116

Type

Journal article

Journal

Thorax

Publication Date

04/2019

Volume

74

Pages

410 - 412

Addresses

Oxford Centre for Respiratory Medicine, Oxford University Hospitals NHS Trust, Oxford, UK.

Keywords

RAMPP Trial collaborators, Humans, Pneumothorax, Monitoring, Physiologic, Prognosis, Treatment Outcome, Hospitalization, Length of Stay, Risk Factors, Prospective Studies, Predictive Value of Tests, Chest Tubes, Adult, Female, Male, Young Adult