Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

Plasmodium falciparum malaria is increasing world-wide, as is resistance to the available antimalarials. On the Thai-Burmese border this problem is most acute in pregnant women, as options for their treatment are even more restricted because of the unknown effects of antimalarials on the foetus. Presented here are the results of descriptive, clinical, drug studies on quinine, mefloquine and artemisinin derivatives for P. falciparum in pregnant women. Mefloquine and quinine have high failure rates for primary and recrudescent infections. Artemisinin-based treatments in pregnant women have proved safe, tolerable and efficacious. However, randomized drug studies with these drugs and other new antimalarials are required to define the true safety and efficacy of these drugs in pregnant women.

Original publication

DOI

10.1080/00034989957709

Type

Conference paper

Publication Date

12/1999

Volume

93 Suppl 1

Pages

S19 - S23

Keywords

Antimalarials, Drug Resistance, Drug Therapy, Combination, Female, Humans, Malaria, Falciparum, Mefloquine, Myanmar, Pregnancy, Pregnancy Complications, Parasitic, Quinine, Sesquiterpenes, Thailand