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Within tumors, macrophage infiltration can promote cancer cell invasiveness and, consequently, metastatic dissemination. In this issue of Developmental Cell, Roh-Johnson et al. (2017) reveal that cytoplasmic transfer from macrophages to melanoma cells correlates with melanoma invasion and arises as a result of intimate cell-cell contact.

Original publication

DOI

10.1016/j.devcel.2017.11.012

Type

Journal article

Journal

Dev Cell

Publication Date

04/12/2017

Volume

43

Pages

543 - 544

Keywords

Animals, Cell Line, Tumor, Cytoplasm, Humans, Macrophages, Melanoma, Neoplasm Invasiveness