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The Wright-Fisher model is considered in the case where the population size is random and the magnitude of the selective advantage of one of the alleles varies with time. The central question addressed is the possibility of ultimate genetic polymorphism. Partial results are obtained in the general case and complete results in the case where the population size and selective advantage are not density dependent. Bounds on the fixation probability are obtained when the selective advantage is constant. © 1985 Springer-Verlag.

Original publication

DOI

10.1007/BF00276544

Type

Journal article

Journal

Journal of Mathematical Biology

Publication Date

01/06/1985

Volume

22

Pages

21 - 29