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Information obtained from genome-wide association studies has cracked open the biology of common chronic diseases by identifying genes that predispose individuals to these disorders. Cadwell et al. (2010) now demonstrate that a viral infection, a toxic insult to the gut, commensal bacteria, and a Crohn's disease susceptibility gene collude to cause inflammatory disease in the mouse gut.

Original publication

DOI

10.1016/j.cell.2010.06.015

Type

Journal article

Journal

Cell

Publication Date

25/06/2010

Volume

141

Pages

1114 - 1116