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Group B streptococcus (GBS) capsular serotypes are major determinants of virulence and affect potential vaccine coverage. Here we report a whole-genome-sequencing-based method for GBS serotype assignment. This method shows strong agreement (kappa of 0.92) with conventional methods and increased serotype assignment (100%) to all 10 capsular types.

Original publication

DOI

10.1128/JCM.03142-15

Type

Journal article

Journal

J Clin Microbiol

Publication Date

05/2016

Volume

54

Pages

1388 - 1390

Keywords

Bacterial Capsules, Genome, Bacterial, Humans, Molecular Typing, Sequence Analysis, DNA, Serotyping, Streptococcus agalactiae