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Differences in virologic response were compared in 32 HIV-infected children with a nelfinavir trough concentration either below (n=7) or above (n=25) 0.8 mg/L. Virologic response at week 48 was observed in 29% of children with subtherapeutic nelfinavir troughs versus 80% in children with therapeutic nelfinavir troughs (P=.02).

Original publication

DOI

10.1016/j.jpeds.2004.04.048

Type

Journal article

Journal

J Pediatr

Publication Date

09/2004

Volume

145

Pages

403 - 405

Keywords

Child, Child, Preschool, Drug Administration Schedule, Female, HIV Infections, HIV Protease Inhibitors, Humans, Male, Nelfinavir