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Diarrhoea contracted whilst travelling in a (sub)tropical country often has an infectious cause. However, dietary changes can also be of importance. We describe the case of a 28-year-old woman, who developed severe coeliac disease during a trip in the Australian outback. The nutritional history revealed that the patient's diet contained more wheat products during her trip than she was used to in Holland. Moreover, the onset of symptoms coincided with a spontaneous miscarriage of an 8-week-old embryo. This correlation has been described in several case reports in the literature. However, the pathophysiologic mechanism behind this correlation is unknown. Some speculative mechanisms are proposed here. Further investigations into this relationship could increase our understanding of the immunopathogenesis of coeliac disease.

Type

Journal article

Journal

Neth J Med

Publication Date

04/1998

Volume

52

Pages

147 - 149

Keywords

Abortion, Spontaneous, Adult, Australia, Celiac Disease, Diet, Female, Humans, Netherlands, Pregnancy, Pregnancy Trimester, First, Travel, Tropical Climate