Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

Before Robert Koch's work in the late nineteenth century, diseases such as tuberculosis and leprosy were widely believed to be inherited disorders. Heritability of susceptibility to several infectious diseases has been confirmed by studies in the twentieth century. Infectious diseases, old and new, continue to be an important cause of mortality worldwide. A greater understanding of disease processes is needed if more effective therapies and more useful vaccines are to be produced. As part of this effort, developments in genetics have allowed a more systematic study of the impact that the human genome and infectious disease have on each other.

Original publication

DOI

10.1038/35103577

Type

Journal article

Journal

Nat Rev Genet

Publication Date

12/2001

Volume

2

Pages

967 - 977

Keywords

Biological Evolution, Communicable Diseases, Genetic Linkage, Genetic Predisposition to Disease, HLA Antigens, Humans