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The relationship between cardiovascular disease and cerebral infarction was analysed in a prospectively assessed post mortem series of 48 demented patients. Hypertension was rare in this group of patients whose mean age was 82.7 y. Atrial fibrillation was the most important underlying cardiac abnormality. It is suggested that atrial fibrillation is more important than hypertension in the aetiology of cerebral infarction in the very aged and that this may be relevant to the pathogenesis of cerebrovascular dementia.

Original publication

DOI

10.1136/pgmj.61.713.201

Type

Journal article

Journal

Postgrad Med J

Publication Date

03/1985

Volume

61

Pages

201 - 204

Keywords

Aged, Atrial Fibrillation, Cerebral Infarction, Circle of Willis, Coronary Disease, Dementia, Female, Humans, Hypertension, Male, Prospective Studies