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The CD8(+) T cell responses to CMV gradually increase in magnitude over time-so-called memory "inflation." In this issue of Immunity, Snyder et al. (2008) examine the dynamics of memory inflation and demonstrate continuous turnover of inflating T cells, drawing on both memory cells and naive cells to replace them.

Original publication

DOI

10.1016/j.immuni.2008.09.008

Type

Journal article

Journal

Immunity

Publication Date

17/10/2008

Volume

29

Pages

520 - 522

Keywords

Animals, Antigens, CD, CD8-Positive T-Lymphocytes, Cytokines, Cytomegalovirus, Cytomegalovirus Infections, Herpesviridae Infections, Humans, Immunologic Memory, Mice, Muromegalovirus