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We have monitored the in vitro sensitivities of Plasmodium falciparum isolates predeployment and during the deployment of artesunate plus amodiaquine treatment in Mlomp, Casamance (southwestern Senegal) during 2000 to 2004. Parasites remained susceptible to both drugs. Chloroquine resistance levels were high but stable. Quinine continues to be effective.

Original publication

DOI

10.1128/aac.50.4.1531-1534.2006

Type

Journal article

Journal

Antimicrobial agents and chemotherapy

Publication Date

04/2006

Volume

50

Pages

1531 - 1534

Addresses

Laboratoire de Parasitologie-Mycologie, Hôpital Hôtel Dieu--Broussais, Université Paris V, France.

Keywords

Animals, Humans, Plasmodium falciparum, Sesquiterpenes, Artemisinins, Amodiaquine, Chloroquine, Antimalarials, Drug Therapy, Combination, Drug Resistance