Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

BackgroundThe Mekong Delta of Vietnam is a hotspot of antimicrobial use (AMU), but there is no information on the quality of the labelling and strength of antimicrobial products used in poultry production.MethodsBased on a large random sample of farms, we identified the 20 most used antimicrobial products in the area, and investigated their antimicrobial active ingredient (AAI) content by UPLC-MS/MS (91 analytical tests).ResultsOnly 17/59 (28.8%) batches contained all AAIs within 10% of the declared strength. Worryingly, 65.0% products provided in their label preparation guidelines for both therapeutic and prophylactic use. Withdrawal times for both meat and eggs were stated in 8/20 (40%) products.ConclusionResults highlight deficiencies in quality and labelling contents that undermine authorities' efforts to discourage inappropriate use of antimicrobials.

Original publication

DOI

10.1002/vms3.189

Type

Journal article

Journal

Veterinary medicine and science

Publication Date

11/2019

Volume

5

Pages

512 - 516

Addresses

Oxford University Clinical Research Unit, Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam.

Keywords

Animals, Chickens, Anti-Bacterial Agents, Chromatography, High Pressure Liquid, Drug Labeling, Vietnam, Tandem Mass Spectrometry